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Jazz Pharmaceuticals Data Scientist Interview Questions & Guide 2026

Data scientist interview prep for Jazz Pharmaceuticals: original practice on experiment design, SQL and metric reasoning, with worked solutions.

The 60-second brief

As a Data Scientist at Jazz Pharmaceuticals, you are at the intersection of advanced analytics and patient-centric innovation. This role is critical to the organization’s mission of transforming the lives of patients with serious diseases. You will work within complex, high-stakes environments where your ability to derive insights from data directly influences clinical development, operational efficiency, and, ultimately, patient outcomes.

Scope your preparation by the data you would actually touch, because the title will not tell you. A seat that lives in event logs and weekly readouts rewards fluency in aggregation and metric definitions; a seat that owns a model in production rewards fluency in train/serve skew, retraining cadence and drift monitoring. The fastest way to find out which one you are interviewing for is to ask what the team shipped last quarter and what it gets paged about.

Focus areas

Reconstruct drug exposure intervals from dispensing records
Correct for claims runout before reporting recent months
Separate censoring from events in time-to-event models

Overview

You will likely operate within teams focused on Biostatistics or Clinical Data Science, where the scale of your work involves managing and interpreting large, sensitive datasets. The complexity of this role lies in your ability to translate technical statistical models into actionable business and clinical strategies. By joining Jazz Pharmaceuticals, you are taking on a role that demands both rigorous analytical precision and the ability to articulate the "why" behind your methodology to non-technical stakeholders.

Where to focus your preparation

Treat the sections below as preparation areas and confirm the format with your recruiter.

Preparation focus

No round sequence has been reported for this company, so work the categories below and confirm the format with your recruiter.

What to demonstrate

Breadth across SQL, experimentation and product reasoning
Ability to state assumptions before choosing a method

How to prepare

Drill the practice exercises below and time yourself
Prepare three quantified stories about decisions you drove

Where candidates lose points

Treating clinical measurements as missing at random

A lab result, a vital sign, or a screening exists because someone ordered it, and ordering tracks suspicion of disease, visit frequency, and site workflow. Imputing the mean or dropping incomplete rows biases the population estimate and can flip the sign of an association, because the untested are systematically healthier or systematically disengaged. The presence indicator is often more predictive than the value, which is a warning sign rather than a feature win: a model that learns test ordering will not transfer to a site with different protocols.

Pre-post evaluation on a high-cost or high-risk cohort

Cohorts selected on an extreme value of the outcome regress toward the mean on their own. Members identified as the top 1 percent of spend in one year spend far less the next, whether or not anyone intervenes, because the selecting year captured both chronic severity and one-off events. A pre-post design on such a cohort will report savings every time. A concurrent comparison group selected by the same rule in the same period, or a regression discontinuity at the selection threshold, is the minimum credible design.

Ignoring interference between units in a marketplace experiment

Ask whether one unit's treatment can change another unit's outcome through shared inventory, a matching pool, a social graph or a common budget. Where it can, randomise at a level that contains the spillover, such as region or time slice, and say explicitly what that costs you in statistical power.

Answering a product-sense question with a list of features

Answer with a decision and the measurement that would settle it: the hypothesis, the primary metric, the guardrails, and the result that would make you not ship. A feature brainstorm cannot be wrong, which is exactly why it earns no points.

Questions & practice

How would you approach a task involving complex clinical data and explain the rationale for your chosen model?

Medium · machine learning and modelling

Approach

Check what information would not exist at prediction time, and exclude it.
Frame the prediction: the label, the moment of prediction, and the action it triggers.
Set a baseline first, so any model has something honest to beat.

Follow-up

How would you choose the decision threshold, and who owns that choice?
What would you monitor after launch to know the model is still valid?

How do you balance the need for model complexity with the requirement for interpretability in a regulated industry?

Medium · machine learning and modelling

Approach

Say how the offline result would be validated online before it is trusted.
Check what information would not exist at prediction time, and exclude it.
Pick an evaluation metric that matches the cost of each error type, not a default.

Follow-up

What would you monitor after launch to know the model is still valid?
Where could label leakage enter this setup?

Build a claims lag triangle and complete recent months

Medium · chain ladder · runout · pivot

medical_claim_line has claim_id, claim_version, frequency_code, service_start_date, paid_date, allowed_amount, claim_status. Using 24 fully mature incurred months, build a development triangle of allowed dollars by incurred month and payment lag in whole months, derive cumulative completion factors by chain ladder, then estimate ultimate allowed for the three most recent incurred months at a stated paid-through date. Deduplicate to surviving claim versions before building the triangle. Return incurred_month, paid_to_date, completion_factor, estimated_ultimate.

Approach

Deduplicate to surviving claim versions and keep paid lines first. A triangle built on all versions develops on adjustment churn rather than on payment timing, and replacements arrive late, so the distortion concentrates in exactly the tail you are trying to estimate.
Compute lag as a whole-month difference between incurred month and paid month, not as day difference divided by 30. Ragged month lengths otherwise shuffle identical claims between lag buckets depending on which month they fall in.
Pivot to incurred_month by lag, cumulate along lag, then form age-to-age factors as the ratio of the column L+1 total to the column L total, summed over incurred months mature enough to have both. Volume weighting is the chain ladder; a simple mean of per-month ratios lets one low-volume month dominate the factor.
Chain the age-to-age factors from each lag to ultimate and invert: completion factor at lag L is the reciprocal of the product of factors from L onward. Apply as estimated_ultimate = paid_to_date / completion_factor.
State the assumption you have just made, which is that the development pattern is stable. It is not, after a claims-system migration, a network change or a processing backlog, and the most recent month's factor is the least reliable because it rests on the fewest observations while carrying the largest adjustment.

Worked solution (35 min)

Deduplicate to surviving versions, drop voids, keep claim_status 'paid', and derive incurred_month from service_start_date and paid_month from paid_date.
lag = (paid_month.year - incurred_month.year) x 12 + (paid_month.month - incurred_month.month); drop negative lags and investigate them separately.
Pivot to a triangle of summed allowed_amount, cumulate along the lag axis, and mask cells past the paid-through date so no cell contains a future payment.
Compute volume-weighted age-to-age factors per lag over the mature rows, then chain them into cumulative completion factors.
Apply the factor for each recent month's current maturity to its paid_to_date and return the four columns.

Expected result: Three rows. Completion is well below 1 at short lag and approaches 1 in the tail; for a mixed medical book a one-month-old incurred month commonly sits far from complete, while a twelve-month-old one is close. Exact values are book-specific, so the reviewable property is monotonicity and the holdout test below, not the numbers themselves.

Verify it yourself

Cumulative completion factors are non-decreasing in lag and converge toward 1 at the tail.
Hold out one fully mature incurred month, apply the factors at each of its intermediate maturities, and confirm each estimate lands within a few percent of its known total.
estimated_ultimate is greater than or equal to paid_to_date for every row.
A pharmacy-only triangle completes far faster than an inpatient-facility-only triangle, which confirms the lag computation is reading real payment timing.

Follow-up

A processing backlog means the last two months developed slower than history. What does your estimate do, and how would you detect that before reporting?
Pharmacy, professional and inpatient facility develop on different clocks. How do you split the triangle, and what breaks if the service mix shifts?
What happens to a PMPM series if someone reports an unadjusted recent month, and in which direction does the error point?

Turn overlapping coverage spans into fractional member-month denominators

Medium · intervals · gaps and islands · denominators

member_enrollment holds span_id, member_id, plan_id, product_type, effective_date and termination_date, which is NULL while the span is active. A member can hold several spans in a year, and back-dated plan changes make spans overlap. Return one row per calendar month of 2025 with total member-months, where a member contributes covered days in the month divided by that month's length, and a day covered by two overlapping spans counts once. Both span endpoints are inclusive. Collapse overlaps with window functions before joining a month calendar, and do not assume one span per member.

Approach

Normalise the open end first. COALESCE(termination_date, DATE '9999-12-31') or clip to the reporting end, because a NULL termination_date makes every BETWEEN comparison unknown and drops exactly the members who are still covered.
Merge overlapping spans per member before the calendar join. Order by effective_date, carry a running MAX of prior termination_date with a frame ending one row before, and open a new island where effective_date exceeds that running max plus one day, which keeps adjacent spans contiguous rather than splitting them.
Clip each merged island to the reporting year, then cross join to a twelve-row month calendar and keep pairs that intersect.
Compute covered days as LEAST(island_end, month_end) minus GREATEST(island_start, month_start) plus one, and divide by the actual length of that month rather than a flat 30, so February and the 31-day months are not distorted.
Sum the fractions by month. Merging after the calendar join also works but forces a DISTINCT over member-days, which stops scaling at population size.

Follow-up

Where does a continuous-enrolment filter with an allowable 45-day gap belong, and how does that change the island boundary rule?
One human appears under two member_ids after a master person index merge. What does that do to member-months, and how would you detect it?
How do you treat a span that terminates on the day it starts, and what does that row usually represent?

Find inpatient encounters with no resulted lab during the stay

Medium · anti-join · null semantics · event matching

encounter holds encounter_id, patient_id, encounter_type, admit_ts, discharge_ts and facility_id. lab_result holds result_id, order_id, patient_id, encounter_id (NULL for outpatient standing orders), loinc_code, specimen_collected_ts, resulted_ts and result_status. Return every inpatient encounter discharged in 2025 with no final or corrected lab_result linked to it. A colleague wrote WHERE encounter_id NOT IN (SELECT encounter_id FROM lab_result) and got zero rows back. Say why, write the correct query, then say what changes when labs must instead be matched on patient_id with the specimen collected between admit_ts and discharge_ts.

Approach

Name the mechanism rather than the symptom. x NOT IN (subquery) expands to x <> y1 AND x <> y2 AND ..., and a single NULL y makes that chain UNKNOWN, never TRUE. Since lab_result.encounter_id is nullable by design for standing orders, this query can only ever return zero rows.
Rewrite as NOT EXISTS, or LEFT JOIN with an IS NULL filter. Both treat a NULL key as no match rather than as unknown. Adding IS NOT NULL inside the NOT IN subquery also works, but NOT EXISTS is the habit that survives someone making another column nullable later.
Put the result_status predicate inside the correlated subquery or the ON clause, not in an outer WHERE. Outside, it turns the anti-join back into an inner join and an encounter whose only labs were cancelled disappears instead of qualifying.
For the timestamp variant, match on patient_id with specimen_collected_ts inside the stay rather than resulted_ts. A specimen drawn an hour before discharge can result the next day, and anchoring on resulted_ts would wrongly call that stay lab-free.
Restrict to encounter_type 'inpatient' and discharge_ts in 2025, and report open encounters with a NULL discharge_ts as a separate count instead of letting the filter swallow them.

Worked solution (20 min)

Demonstrate the cause: SELECT COUNT(*) FROM lab_result WHERE encounter_id IS NULL returns a non-zero number.
Write the NOT EXISTS version with result_status IN ('final','corrected') inside the correlated subquery.
Write the LEFT JOIN version with the same predicate in the ON clause and WHERE l.result_id IS NULL, then compare counts.
Build the timestamp variant joining on patient_id with specimen_collected_ts >= admit_ts AND < discharge_ts.
Report both counts side by side and explain which encounters differ between the two definitions.

Expected result: One row per qualifying inpatient encounter with encounter_id, patient_id, facility_id, admit_ts and discharge_ts. The count is strictly below total 2025 inpatient discharges and strictly above zero, while the NOT IN version returns exactly zero rows.

Verify it yourself

NOT EXISTS and LEFT JOIN with IS NULL return identical row counts.
Adding AND encounter_id IS NOT NULL inside the NOT IN subquery reproduces the NOT EXISTS count exactly.
No returned encounter_id appears anywhere in lab_result with result_status in ('final','corrected').
The patient-and-timestamp variant returns fewer encounters than the encounter_id variant, since it also catches labs whose encounter link is missing.

Follow-up

Write the LEFT JOIN form and say exactly where the result_status predicate must sit for the two forms to agree.
How would you separate encounters whose only labs were cancelled from encounters with no lab rows at all?
Some encounters carry member_id NULL because the person index did not match. What does that do to a payer-side version of this measure?

When provided with a dataset, what is your initial process for identifying outliers and ensuring data integrity?

Medium

Approach

Clarify what is being asked and what a complete answer would contain.
State your assumptions explicitly before working the problem.
Say what you would check first and why it is the highest-information step.

Follow-up

What assumption would you test first?
How would you know your answer was wrong?

Decompose risk-adjusted cost per member into owned leaf metrics

Hard · metric tree · price volume mix · coding intensity · ownership

Build a metric tree, at most four levels deep, from risk-adjusted allowed PMPM down to leaves an owner can move. Data: medical_claim_line (allowed_amount, units, procedure_code, place_of_service_code, service_start_date, claim_version, frequency_code), pharmacy_claim (allowed_amount, days_supply, is_generic, formulary_tier, reversal_flag), member_enrollment (coverage spans, prospective_risk_score). Give the arithmetic identity each split rests on, the leading indicator at each leaf, and identify the one node where the arithmetic is exact but the attribution is not.

Approach

State the base identity before drawing anything. Allowed PMPM equals total allowed over member-months, and it decomposes exactly by service category c as the sum over c of (units_c / member-months) times (allowed_c / units_c). Utilization per member-month and allowed per unit, summed across categories, so category mix is inside the sum rather than a separate hand-wave.
Give the change decomposition too, because the tree will be read on deltas: the change in PMPM equals the sum over categories of (change in utilization times base price) plus (base utilization times change in price) plus (change in utilization times change in price). The third term is the interaction, it is not noise, and an analysis that drops it will not reconcile.
Build the medical branch to leaves with owners: inpatient admits per 1,000 member-months and allowed per admit (with DRG case mix as the sub-split), ambulatory visits per 1,000 and allowed per visit split by place_of_service_code, and emergency visits per 1,000 and allowed per visit. Prepare the data with version dedup to the surviving claim_version before a single dollar is summed, since frequency_code 7 replaces and 8 voids.
Build the pharmacy branch on 30-day equivalents: scripts_30 equals the sum of days_supply over 30 on unreversed fills, so pharmacy PMPM equals (scripts_30 per member-month) times (allowed per 30-day script). Split the price term exactly as g times the generic price plus (1 minus g) times the brand price, where g is the generic dispensing rate, which makes generic substitution and unit price separable leaves with different owners.
Attach one leading indicator per leaf: prior-authorization approvals and elective surgical bookings ahead of inpatient admits, contract effective dates ahead of allowed per unit, site-of-service steering ahead of the ambulatory place_of_service mix, new-to-brand starts and formulary tier placement ahead of pharmacy price.
Name the node where arithmetic is exact but attribution is not: the risk-adjustment denominator. Dividing by the population mean prospective_risk_score is exact arithmetic, but the score is built from coded diagnoses, so more complete coding raises the denominator and lowers risk-adjusted PMPM with no change in care delivered. Carry raw PMPM, the mean risk score trend and a coding-intensity measure such as diagnoses per member-year beside it, permanently.

Worked solution (45 min)

Write the base identity and the three-term change decomposition on paper first, and confirm the terms sum to the total change on a two-category toy example before touching real data.
Specify the preparation rules that precede any aggregation: dedup medical_claim_line to the surviving version per claim_id using claim_version and frequency_code, drop both rows of every reversed pharmacy pair, and build member-months from coverage spans with partial months counted fractionally.
Draw the medical branch and the pharmacy branch to leaf level, writing the identity beneath each split rather than only the metric name.
Write the generic-dispensing split as the exact price identity and confirm it reproduces the observed allowed per 30-day script.
Attach one leading indicator and one named owning function to each leaf.
Write the caveat on the risk-adjustment node, including the two companion series that must be published with it.

Expected result: A four-level tree rooted at risk-adjusted allowed PMPM, splitting by service category into utilization per member-month and allowed per unit, with an inpatient sub-split on DRG case mix, an ambulatory sub-split on place_of_service_code, and a pharmacy branch on 30-day equivalents whose price term is split exactly by generic dispensing rate; each leaf carries a named owner and a leading indicator; and the risk-adjustment denominator is flagged as exact arithmetic with unreliable attribution, published alongside raw PMPM, the mean risk score trend and a coding-intensity series.

Verify it yourself

Reconcile the leaves back to the root: the summed category contributions must equal total allowed PMPM to within rounding, and the three change terms must sum to the observed period change.
Recompute total allowed with and without version dedup. Any gap is the double-counted adjusted claims the tree would otherwise attribute to real utilization.
Verify the pharmacy price identity numerically: generic dispensing rate times generic price plus its complement times brand price should reproduce the observed blended allowed per 30-day script.
Hold care constant and simulate a 5 percent rise in mean prospective_risk_score. Risk-adjusted PMPM should fall by roughly the same proportion, which is the attribution problem made visible.

Follow-up

Utilization is flat and allowed per unit is flat, yet PMPM rose 4 percent. Name every place the increase can be hiding.
Your member-month denominator came from coverage spans that overlap across products for some members. What does that do to PMPM, and how do you decide whether to deduplicate?
Which leaf would you refuse to put on a team's scorecard, and why?

Allowed PMPM fell fourteen percent in three months

Easy · claims runout · completion factors · incurred vs paid

Allowed PMPM in the monthly series fell from $412 to $354 over the three most recent incurred months, and leadership wants to announce the saving. You have medical_claim_line (allowed_amount, service_start_date, received_date, paid_date, claim_id, claim_version, frequency_code, place_of_service_code), pharmacy_claim (allowed_amount, fill_date, reversal_flag) and member_enrollment coverage spans. The chart carries no paid-through date. Work out how much of the fall survives completion, and hand back a restated series with an explicit paid-through date and the completion factors you applied.

Approach

Get the paid-through date first and put it on the chart. Without it the series is uninterpretable, because every incurred month is a different age.
Build a lag triangle: for each incurred month, cumulative allowed_amount by the number of months between service_start_date and paid_date, on surviving claim versions only (drop frequency_code 8 voids and keep the highest claim_version per claim_id).
Estimate development factors separately for pharmacy fills, professional lines and inpatient facility lines. Pharmacy adjudicates within days, professional within weeks, inpatient facility over months, so one blended factor understates the correction on the newest month and overstates it on the oldest.
Gross each of the last three incurred months up by the reciprocal of its cumulative development factor, using factors fitted on months that have already fully run out.
Rebuild the denominator independently as member-months from coverage spans. Member-months are complete on day one, so if the denominator also shows a lag pattern the enrollment file is late, which is a different bug with a different fix.
Restate the series, mark the last three months as estimated, and report the residual movement after completion as the only part worth investigating.

Follow-up

The completed series still shows a three percent fall. What do you look at next, and in what order?
How would you detect that the fall is a mix shift toward cheaper services rather than lower volume?
A contract settles on this number at a fixed paid-through date. What do you owe the other party about the estimate you just made?

Suggested practice checklist

For someone who can already write the query and train the model but stalls when asked what to measure or whether a change is worth making. Metric definition and case structure come first; the technical work is kept as maintenance rather than the centre of the week.

Day 1 — Metric anatomy

For three products you use daily, write one primary metric, two input metrics that plausibly move it, and one guardrail that would catch a cheap way of moving the primary at the cost of the product.
For one of them, specify the metric precisely enough that two analysts would return the same number: numerator, denominator, unit of observation, time window, and how returning and deleted accounts are treated.
Pick a ratio metric and write what happens to it when the denominator shrinks for reasons unrelated to the numerator, with a concrete example of that happening.

Deliverable: A one-page metric tree for one product, with the primary metric written as an unambiguous spec.

Day 2 — Diagnosing a drop without guessing

Take the prompt "weekly active users fell 8 percent week over week" and write the segmentation plan before proposing any cause: platform, region, tenure cohort, acquisition channel, and whether the movement sits in the numerator or in a changed denominator.
List the instrumentation failures that manufacture fake drops (a client release that stopped firing an event, a bot filter change, a shifted date boundary or timezone) and write the query that rules out each one.
Rehearse stating the boring explanations first, seasonality and day-of-week composition, before reaching for a product cause.

Deliverable: A drop-diagnosis checklist short enough to recite from memory in under a minute.

Day 3 — Should we build it

Take a feature idea and write it as a bet: what you believe is true, what would have to be true for it to pay off, the metric that would confirm it, and the effect size that would justify the engineering cost.
Size the opportunity top-down and bottom-up, then reconcile the two numbers in writing instead of quoting whichever is friendlier.
Write the counter-metric that would make you kill the feature even if it wins on the primary metric.

Deliverable: A one-page product memo ending in a decision rather than a list of considerations.

Day 4 — The places aggregate numbers lie

Construct a Simpson's paradox numerically: two segments where the treatment wins within each segment yet loses overall, and identify the shift in segment weights that causes it.
Take a heavy right-tailed quantity such as revenue per user and write why the mean is the wrong summary, which percentile you would report instead, and what a moving mean with a stable median tells you.
Write your definition of a session for the product from day one, then name two real behaviours it misclassifies.

Deliverable: One page holding a worked Simpson's paradox table and a session definition with its two known failure cases.

Day 5 — Technical maintenance, aimed at metrics

Solve four timed SQL prompts that all end in a ratio metric, so the question of grain stays live in every answer.
Compute a 95 percent confidence interval for a proportion on a small sample, and state why the normal approximation is unreliable when either np or n(1 minus p) falls below roughly 10, along with which interval you would use instead.
Take one metric from your day-one tree, write the query that computes it correctly, then write the query that computes it wrong in the most plausible way and explain how you would notice.

Deliverable: Four solved prompts plus a matched correct and plausible-wrong query for one metric.

Day 6 — Turning engineering work into data science stories

Write three project stories as situation, decision, trade-off, outcome, each carrying one number and one thing you got wrong.
For the story you will lead with, prepare an answer to "what would you do differently" that names a decision you made, not a constraint you were handed.
Practise the sentence that reframes a systems project as a question project: the question the work answered, ahead of the pipeline it shipped.

Deliverable: Three written stories with the lead story delivered aloud and timed under four minutes.

Day 7 — Mock case and gap list

Run a 40-minute mock case with someone playing a product manager who pushes back on your metric choice, and record it.
Listen back and mark every moment you proposed a solution before the success metric existed.
Rewrite those moments as the question you should have asked, and rehearse the first 90 seconds of the case until scoping comes before solving.

Deliverable: A recorded case plus a rewritten opening 90 seconds.

Where your data came from

Data people depend on systems owned by other teams, and much of the job is negotiating for instrumentation, access, or a fix to a broken pipeline. Prepare an example of getting something changed upstream that you did not control. Describe what you asked for, what you traded, and how you worked while you waited.

Can you describe a time you had to justify a specific statistical approach to a stakeholder who lacked a technical background?

Medium · behavioural and stakeholder questions

Approach

Pick a story where you drove the decision, not one where you observed it.
Close with what you would do differently, concretely.
State the situation in two sentences and spend the rest on your reasoning.

Follow-up

What would you do differently if you ran that project again?
What did you decide not to do, and why?

Disagree with a product manager about an adherence nudge

Medium · immortal time · confounding · disagreement

A product manager proposes shipping a refill-reminder feature to the whole member base, citing an internal analysis: members with 12-month proportion of days covered at or above 0.80 had 31 percent fewer admissions than members below it. The roadmap date is three weeks out and engineering is scoped. You believe the comparison builds survival and continuous coverage into the exposure definition, and is separately confounded by the kind of member who refills on time. Deliverable: what you say in the room, what you send afterwards, and the smallest study you would accept as sufficient to ship.

Approach

The probe is whether you can be specific and non-territorial at once. A disagreement that arrives as 'the analysis is flawed' costs you the room; one that names a mechanism and offers a cheaper path keeps it.
Name the two defects separately, because they have different fixes. Classifying a member as adherent over 12 months requires them to stay alive and stay covered for those 12 months, and that guaranteed event-free interval is assigned to the adherent group. Separately, members who refill on schedule differ from those who do not in ways claims never record.
Show rather than assert. Rerun the same comparison as a landmark analysis: classify adherence over days 1 to 90, start follow-up at day 91 for everyone still enrolled and event-free, and report how much of the 31 percent survives.
Separate the association claim from the intervention claim out loud. Nothing in the analysis speaks to whether a reminder changes refill behaviour, which is the actual product question and is separately testable.
Offer the shippable path: a randomised holdout on a subset with proportion of days covered as the primary endpoint, powered on the plausible effect of a reminder rather than on the 31 percent, with a stated read date.

Follow-up

The landmark rerun still shows a 20 percent difference. Do you ship?
The product manager says a holdout delays launch. How do you cost that argument?
What primary endpoint do you choose, and why not admissions?

Push back on an over-broad extract without blocking the work

Hard · minimum necessary · de-identification · governance

A researcher asks for a one-off extract covering 12,000 members: member_id, date of birth, five-digit residential postal code, full lab_result rows including value_text, and clinical note text, held on their laptop for a retrospective analysis of one lab analyte over time. They describe it as de-identified because names are excluded. A flat refusal is not an acceptable answer. Deliverable: the column list you will actually provide with a justification per retained field, the sentence explaining why free text defeats an enumerated-identifier approach, your small-cell rule for the published stratification, and what you deliver this week.

Approach

The probe is whether privacy is a design skill for you or a compliance reflex. Flat refusal and unquestioned fulfilment both fail, for opposite reasons.
Reconstruct the analysis from the research question rather than from the request. A longitudinal trend in one analyte needs a stable pseudonymous subject key, the analyte's loinc_code, value_numeric, units, the reference bounds, and a date. It does not need names, notes, or a precise birth date.
Replace each identifier with the least precise version that still answers the question: a salted per-study pseudonym instead of member_id, age in years or an age band instead of date of birth, a consistent per-subject date offset if only intervals matter, and a coarser geography than five-digit postal code.
Explain the free-text problem in one sentence. Removing an enumerated list of identifier fields does not de-identify a note, because notes carry names, relationships, employers, dates and rare clinical detail in prose, so only a reviewed extraction into structured fields or a formal statistical determination addresses it.
Set the publication rule before the analysis runs. Suppress cells below a stated threshold and suppress complements too, because a reader holding a row total and all but one cell recovers the suppressed count by subtraction.
Keep them moving. Deliver the reduced extract into a controlled environment this week rather than onto a laptop, and offer to derive any note-based variable yourself as a structured flag so they never need the prose.

Follow-up

They say the age band loses resolution their model needs. What do you do?
How do you set the suppression threshold, and who signs off on it?
The analysis later needs linking to a second data source. What changes?